Toshiaki Kume Selected Research

Dimethyl Fumarate

1/2016

Protective Effect of Dimethyl Fumarate on an Oxidative Stress Model Induced by Sodium Nitroprusside in Mice.

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Toshiaki Kume Research Topics

Disease

21	Alzheimer Disease (Alzheimer's Disease) 10/2023 - 08/2003
13	Parkinson Disease (Parkinson's Disease) 01/2020 - 01/2003
8	Cerebral Hemorrhage 01/2016 - 04/2006
6	Cognitive Dysfunction 10/2023 - 12/2010
6	Ganglion Cysts (Ganglion) 08/2009 - 01/2003
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 12/2003
5	Ischemia 01/2014 - 11/2002
4	Brain Injuries (Brain Injury) 08/2010 - 07/2004
4	Neuroblastoma 01/2010 - 03/2005
3	Chronic Pain 03/2024 - 01/2019
3	Pain (Aches) 03/2024 - 08/2023
3	Infarction (Infarctions) 01/2014 - 05/2008
3	Reperfusion Injury 01/2014 - 01/2007
3	Necrosis 10/2011 - 09/2003
2	Liver Cirrhosis (Hepatic Cirrhosis) 04/2024 - 02/2023
2	Pruritus (Itching) 02/2022 - 01/2022
2	Contact Dermatitis (Eczema, Contact) 01/2022 - 09/2019
2	Memory Disorders (Memory Loss) 01/2017 - 09/2012
2	Brain Ischemia (Cerebral Ischemia) 09/2013 - 05/2008
2	Hematoma 10/2011 - 07/2007
2	Wounds and Injuries (Trauma) 01/2010 - 04/2006
1	Liver Diseases (Liver Disease) 02/2023
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2022
1	Hypoxia (Hypoxemia) 10/2022
1	Hypersensitivity (Allergy) 01/2022
1	Dermatitis 01/2022
1	Ischemic Stroke 09/2021
1	Encephalitis (Encephalitis, Rasmussen) 01/2021
1	Inflammation (Inflammations) 01/2020
1	Lewy Body Disease (Lewy Body Dementia) 11/2019
1	Brain Diseases (Brain Disorder) 01/2017
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2014
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 09/2013
1	Tauopathies 09/2012
1	Paralysis (Palsy) 10/2011

Drug/Important Bio-Agent (IBA)

10	Amyloid (Amyloid Fibrils)IBA 10/2023 - 12/2010
10	Proteins (Proteins, Gene)FDA Link 10/2023 - 08/2010
7	Donepezil (Aricept)FDA LinkGeneric 01/2019 - 08/2003
7	Thrombin FDA Link 10/2011 - 04/2006
6	Dopamine (Intropin)FDA LinkGeneric 01/2011 - 10/2005
6	Glutamic Acid (Glutamate)FDA Link 01/2010 - 07/2004
4	Cholinesterase Inhibitors (Anticholinesterases)IBA 05/2017 - 09/2006
4	Proteasome Endopeptidase Complex (Proteasome)IBA 11/2015 - 02/2007
4	serofendic acidIBA 01/2014 - 01/2007
4	Retinaldehyde (Retinal)IBA 03/2006 - 01/2003
3	Therapeutic UsesIBA 11/2022 - 03/2009
3	Oxygen (Dioxygen)IBA 09/2021 - 10/2004
3	AntioxidantsIBA 01/2020 - 10/2005
3	AcetylcholinesteraseIBA 01/2019 - 08/2003
3	ParaquatIBA 11/2015 - 01/2011
3	UbiquitinIBA 11/2015 - 02/2007
3	HerbicidesIBA 11/2015 - 01/2011
3	Tacrine (Cognex)FDA Link 01/2010 - 09/2006
3	N-Methylaspartate (NMDA)IBA 03/2006 - 01/2003
2	CalciumIBA 01/2024 - 02/2007
2	AcidsIBA 02/2023 - 11/2004
2	CurcuminIBA 11/2022 - 01/2017
2	LipopolysaccharidesIBA 01/2021 - 07/2009
2	Heme Oxygenase-1IBA 01/2020 - 07/2010
2	SynucleinsIBA 11/2019 - 01/2016
2	EnzymesIBA 01/2017 - 11/2004
2	Collagenases (Collagenase)FDA Link 10/2011 - 07/2007
2	Blood Coagulation Factors (Coagulation Factor)IBA 08/2010 - 01/2009
2	Mitogen-Activated Protein KinasesIBA 08/2010 - 07/2007
2	Serine Proteases (Serine Protease)IBA 08/2010 - 04/2006
2	Glutathione (Reduced Glutathione)IBA 02/2007 - 10/2005
2	quinone (benzoquinone)IBA 10/2005 - 03/2005
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2005 - 12/2003
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 11/2004 - 11/2002
2	Glucose (Dextrose)FDA LinkGeneric 11/2004 - 10/2004
2	Neuroprotective AgentsIBA 04/2003 - 01/2003
1	Indicators and Reagents (Reagents)IBA 04/2024
1	phytobacteriomycin (PBM)IBA 03/2024
1	Analgesics (Analgesic Drugs)IBA 01/2024
1	gadolinium ethoxybenzyl DTPA FDA Link 02/2023
1	Human Serum Albumin FDA LinkGeneric 02/2023
1	GadoliniumIBA 02/2023
1	pyrazoleIBA 11/2022
1	Histamine (Histamine Dihydrochloride)FDA Link 02/2022
1	Adenosine Triphosphate (ATP)IBA 02/2022
1	Irritants (Vesicants)IBA 01/2022
1	Surface-Active Agents (Surfactants)IBA 01/2022
1	panaxytriolIBA 01/2021
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 02/2020
1	Transcription Factors (Transcription Factor)IBA 01/2020
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2020
1	2',3'-dihydroxy-4',6'-dimethoxychalconeIBA 11/2019
1	Picryl Chloride (Trinitrochlorobenzene)IBA 09/2019
1	Freund's AdjuvantIBA 01/2019
1	Dimethyl FumarateIBA 01/2016
1	Monoclonal AntibodiesIBA 01/2016
1	ATP dependent 26S protease (26S proteasome)IBA 11/2015
1	Matrix Metalloproteinases (MMPs)IBA 01/2014
1	RotenoneIBA 09/2012
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 09/2012

Therapy/Procedure

3	Intravenous Administration 01/2017 - 09/2013
2	Low-Level Light Therapy (LLLT) 03/2024 - 08/2023
2	Therapeutics 07/2009 - 01/2007
2	Intravitreal Injections 08/2003 - 01/2003
1	Immunotherapy 01/2017